Course
Live
Intermediate
Dr. Omics
Specialised Course of Practical Phylogenetics: Multiple Sequence Alignment and Phylogenetic Tree Analysis Using MEGA
Master hands-on phylogenetic analysis using MEGA, from multiple sequence alignment and model selection to phylogenetic tree construction and interpretation.
- 5.0/5
- English
- Updated Sep 2026
About this course
Develop practical skills in molecular phylogenetics through our specialised course on Multiple Sequence Alignment and Phylogenetic Tree Analysis Using MEGA. This hands-on course covers sequence preparation, multiple sequence alignment, alignment evaluation and editing, evolutionary distance calculation, substitution model selection, and phylogenetic tree construction using commonly applied methods in MEGA. Participants will learn how to visualize, analyze, and interpret phylogenetic trees to understand evolutionary relationships among genes, proteins, or organisms.
What you will learn
Understand the fundamental concepts of molecular evolution and phylogenetics.
Prepare and manage DNA or protein sequence datasets for phylogenetic analysis.
Perform multiple sequence alignment using MEGA.
Evaluate and refine sequence alignments.
Calculate evolutionary distances between sequences.
Select appropriate evolutionary models for analysis.
Construct phylogenetic trees using different methods.
Visualize, customize, and interpret phylogenetic trees.
Analyze evolutionary relationships from real biological sequence datasets.
Skills you will gain
MEGA software
multiple sequence alignment
DNA sequence analysis
protein sequence analysis
sequence editing
alignment evaluation
evolutionary distance analysis
substitution model selection
phylogenetic tree construction
Neighbor-Joining
Maximum Likelihood
phylogenetic tree visualization
tree interpretation
molecular evolution
evolutionary relationship analysis
Course curriculum
1 moduleWhat you need to start
- Basic understanding of molecular biology and genetics.
- Familiarity with DNA and protein sequences.
- Basic knowledge of bioinformatics is helpful but not mandatory.
- No prior experience with MEGA is required.
Who this course is for
- B.Sc./M.Sc. students in Bioinformatics, Biotechnology, Microbiology, Biochemistry, Genetics, and Life Sciences.
- PhD scholars and research students working with sequence data.
- Students interested in evolutionary biology and phylogenetics.
- Researchers performing DNA or protein sequence analysis.
- Bioinformatics beginners seeking practical experience in phylogenetic analysis.
