Course Self Paced All Levels Dr. Omics

CRISPR Informatics: Designing & Analyzing Gene Edits- recorded courses

Master computational genome editing pipelines to design highly specific guide RNAs. Deploy bioinformatics data workflows to analyze structural modifications and eliminate off-target mutations.

  • 5.0/5
  • English
  • Updated Aug 2026
CRISPR Informatics: Designing & Analyzing Gene Edits- recorded courses

About this course

Welcome to an advanced self-paced learning experience designed to establish your expertise in computational genome engineering and sequence informatics. As biotechnology shifts toward precise molecular therapeutics, mastering the digital side of genetic modification has become a critical requirement for researchers worldwide. This technical program equips you with industry-standard skills to model, design, and validate genome modifications before running wet-lab experiments. Throughout this training, you will learn to navigate specialized biological databases to retrieve precise target genes and design optimal guide RNAs. You will explore advanced computational scoring functions that calculate targeting efficiencies and pinpoint potential off-target liabilities across full genomes. Furthermore, the curriculum emphasizes data analytics pipelines used to assess high-throughput sequencing data generated after gene-editing events. By combining core structural biology concepts with modern AI-driven gRNA predictive tools, you will gain a deep understanding of how machine learning models enhance target specificity. Step confidently into the dry-lab environment, add high-demand bioinformatics credentials to your portfolio, and accelerate your research career in global biotechnology.

What you will learn

Navigate structural genomics databases to locate target genes and analyze chromosomal sequence architecture.
Design highly specific guide RNAs (gRNAs) using web platforms and automated command-line software libraries.
Implement statistical alignment models to predict, evaluate, and minimize off-target mutation risks.
Parse and interpret high-throughput Next-Generation Sequencing (NGS) data to measure cellular gene-editing efficiency.
Leverage modern machine learning algorithms and predictive AI scoring models to optimize synthetic knock-out and knock-in designs.

Skills you will gain

CRISPR Informatics Genomics Target-Design Sequencing Bioconductor Bio-Pipelines Data-Cleaning Off-Targeting Simulation
Certification

Available

Issued by Dr. Omics

Course curriculum

1 module

  • 1.Introduction to CRISPR-cas9
  • 2.Understanding of SRA database
  • 3. Quality Control of Reads using fastqc
  • 4. Trimming and Filtering Reads using fastp
  • 5. Genome Indexing and Read Alignment using bwa
  • 6. Variation calling using GATK
  • 7. Predicting Variant Effects
  • 8. Variation Visualization (IGV)

What you need to start

  • A foundational understanding of general genetics, inheritance principles, and the molecular central dogma (DNA to RNA).
  • Basic familiarity with using web-based tools and navigating standard files; no advanced software engineering skills are mandatory.
  • A personal laptop or desktop computer with a steady internet connection to access online cloud computing portals.

Who this course is for

  • Bioinformaticians and Data Analysts aiming to specialize in the rapidly growing field of therapeutic genome analytics.
  • Molecular Biologists and Wet-Lab Scientists wanting to eliminate trial-and-error by mastering computational guide pre-design workflows.
  • Biotechnology Students and Postgraduates seeking industry-ready technical skills to secure positions in advanced gene therapy firms.
  • AI Research Engineers looking to deeply understand the multi-omic sequence data structures that feed modern predictive genome-editing models
INR

₹3999

₹5000 20% off
USD

$45

$50 10% off

Indian learners pay in INR; international learners are billed in USD.

Enroll for International Students

Paying from outside India? Use this link to complete your payment.

This course includes
  • Format Self Paced
  • Level All Levels
  • Language English
  • Modules 1
  • Access 3 months
  • Certificate Yes
  • Provider Dr. Omics
  • Certificate
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