Dr. Omics Education;

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Course Requirements

Motivation to Learn: A strong desire to engage with and understand the material.
Basic Knowledge: Familiarity with biology and molecular biology concepts.
Interest in Technology: Eagerness to learn about the latest technologies in Next-Generation Sequencing (NGS).
Software: Free software will be utilized, so no additional software purchases are necessary.
Hardware: A laptop with a minimum of 4GB RAM and 100GB of hard disk space.

Course Description

Introduction to whole genome sequencing and the importance of de novo assembly in genomics.
Learn the basics of de novo assembly techniques and algorithms used in genome assembly projects.
Gain hands-on experience with popular de novo assembly tools like SPAdes, Canu, and Velvet.
Explore quality control methods for evaluating assembly quality, including N50, contig lengths, and coverage.
Learn how to annotate assembled genomes and perform functional analysis to identify genes and pathways.
Interpret the results of whole genome de novo assemblies for downstream applications in evolutionary biology, disease research, and biodiversity studies.

Course Outcomes

Understand the fundamentals of whole genome sequencing and the role of de novo assembly in genome analysis.
Apply de novo assembly algorithms and tools to assemble genomes from raw sequencing data.
Evaluate the quality of genome assemblies using key metrics such as N50, GC content, and coverage.
Conduct genome annotation to identify genes, regulatory elements, and functional pathways.
Use bioinformatics tools for visualizing assembly data and interpreting biological findings.
Gain the skills to apply whole genome de novo assembly techniques in research areas such as evolutionary genomics, functional genomics, and disease studies.

Rules & Regulations

Attendance: Students must watch at least 75% of the recorded sessions to meet the minimum participation criteria.
Feedback and Communication: Maintain open communication with instructors for clarifications and actively provide constructive feedback to enhance the course experience.
Certification: A certificate of completion will be awarded to students who fulfill the attendance requirement and complete all necessary course components.

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