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Instructor Name

Dr.Omics

Category

Internships

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Course Requirements

  • Motivation to Learn: A strong desire to engage with and understand the material.
  • Basic Knowledge: Familiarity with biology and molecular biology concepts.
  • Interest in Technology: Eagerness to learn about the latest technologies in Next-Generation Sequencing (NGS).
  • Software: Free software will be utilized, so no additional software purchases are necessary.
  • Hardware: A laptop with a minimum of 4GB RAM and 100GB of hard disk space.

Course Description

  • Introduction to GWAS (Genome-Wide Association Studies): Understanding the role of GWAS in identifying genetic variants linked to diseases.
  • Pharmacogenomic Applications in Drug Discovery: Exploring how pharmacogenomics is used to develop personalized drug therapies.
  • Pharmacogenomics in Cancer Treatment: Tailoring cancer treatments based on individual genetic profiles.
  • Variant Calling Analysis using GATK: Techniques for detecting and analyzing genetic variants using the Genome Analysis Toolkit (GATK).

Course Outcomes

  • Master GWAS Techniques: Develop skills in conducting and interpreting genome-wide association studies.
  • Pharmacogenomics in Drug Development: Understand the integration of pharmacogenomics in creating personalized drugs.
  • Personalized Cancer Treatment: Learn to apply pharmacogenomics for developing individualized cancer therapies.
  • Expertise in Variant Calling: Gain proficiency in variant detection and analysis using GATK.
  • Advanced Analytical Skills: Enhance your ability to analyze and interpret complex genetic data.
  • Practical Application: Apply learned techniques in real-world pharmacogenomics research and clinical settings.

Rules & Regulations

  • Attendance and Participation: Maintain a minimum of 75% attendance. Regular assessments and attendance contribute to performance evaluation.
  • Discipline: Maintain punctuality and respect in live classes. Engage actively and interact respectfully with instructors and peers.
  • Course Fee Payment: Pay course fees on time to avoid suspension or cancellation of access.
  • Assignments and Project: Complete assignments and projects sincerely and submit them on time.
  • Feedback and Communication: Maintain open communication with instructors and provide constructive feedback.
  • Certification: A certificate will be awarded upon course completion.

Course Curriculum DOWNLOAD BROCHURE

1 Sequencing Technologies its applications, Introduction to NGS and DNAseq,
1 Hour


1 Introduction to Drug Development
1 Hour


2 Compound Databases in Drug Discovery
1 Hour


3 Principles of Pharmacokinetics
1 Hour


4 Pharmacodynamics and Drug Action
1 Hour


5 Drug Metabolism and Pharmacokinetic Modeling
1 Hour


6 Pharmacovigilance and Drug Safety
1 Hour


7 Pharmacogenomics and Drug Target Selection
1 Hour


8 Pharmacogenomics in Clinical Trials
1 Hour


9 Pharmacogenomics for Predicting Drug Efficacy and Safety
1 Hour


10 Application of NOMAD in Pharmacogenomics
1 Hour


1 Genetic Basis of Cancer
1 Hour


2 Genetic Variations Impacting Cancer Drug Response
1 Hour


3 Targeted Therapies and Biomarkers
1 Hour


4 Genomic Profiling Techniques
1 Hour


5 Cancer Genomics Databases(The Cancer Genome Atlas - TCGA)
1 Hour


6 Genomic Alterations in Drug Response
1 Hour


7 Functional Genomics in Cancer Research(CRISPR/Cas9 technology)
1 Hour


8 Development of biological drugs andcell/animal models.
1 Hour


9 Clinical trial implications of Pharmacogenomics in Oncology:
1 Hour


10 Case studies illustrating how genetic variations impact treatment outcomes in specific cancer types
1 Hour


1 Sequencing Technologies its applications, Introduction to NGS and DNA seq
1 Hour


2 Basic Terminologies in NGS
1 Hour


3 Understanding of SRA database
1 Hour


4 Tools installation in Linux for Variation Calling
1 Hour


5 Quality control (FastQC)
1 Hour


6 Trimming of Reads (Trimmomatic)
1 Hour


7 Indexing of Genome (BWA) and Alignment of Reads (BWA)
1 Hour


8 Variation calling using GATK
1 Hour


9 Variant Effect Prediction(VEP)
1 Hour


10 Variation Visualization (IGV)
1 Hour


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PHARMACOGENOMICS and PERSONALISED MEDICINE( 2 MONTHS )

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